Introduction:
Are you craving the ultimate comfort food that combines two beloved classics—mac and cheese, and meatloaf? This Mac and Cheese Meatloaf Casserole recipe is your answer! It’s a mouthwatering, indulgent dish that takes the creamy, cheesy goodness of macaroni and cheese and pairs it with the hearty, savory flavors of meatloaf. Whether you’re cooking for a family dinner, a potluck, or simply treating yourself to an unforgettable meal, this casserole will hit all the right notes. Read on for step-by-step instructions, ingredient lists, and pro tips to make this delightful fusion of flavors. Ready to elevate your comfort food game? Let’s dive into this incredible recipe!

What is Mac and Cheese Meatloaf Casserole?
Mac and Cheese Meatloaf Casserole is a hybrid dish that combines two comfort food staples: macaroni and cheese and traditional meatloaf. The base of this casserole is a well-seasoned meatloaf that’s topped with a rich, creamy layer of homemade mac and cheese. The result is a warm, satisfying meal that's perfect for any occasion. The flavors blend beautifully, offering the savory notes of ground beef and seasonings alongside the creamy texture and cheesy taste of macaroni.
Ingredients List for the Meatloaf:
- 1 pound ground beef (85% lean is ideal for flavor)
- ½ pound ground pork (optional, adds extra juiciness)
- 1 small onion, finely diced
- ½ cup breadcrumbs (preferably plain or Italian-seasoned)
- ¼ cup milk (to keep the meatloaf moist)
- 1 large egg
- 1 tablespoon Worcestershire sauce
- 2 cloves garlic, minced
- ½ teaspoon salt
- ¼ teaspoon ground black pepper
- 1 teaspoon dried oregano or Italian seasoning
- 1 tablespoon ketchup (optional, for a slight sweetness)
Ingredients List for the Mac and Cheese:
- 2 cups elbow macaroni (or any pasta of your choice)
- 2 cups shredded sharp cheddar cheese (feel free to mix with other cheeses like Gouda or mozzarella)
- ¼ cup unsalted butter
- ¼ cup all-purpose flour
- 2 cups whole milk (for a creamier sauce)
- ½ teaspoon mustard powder (optional, adds a nice tang)
- ½ teaspoon garlic powder
- Salt and pepper to taste
- ½ cup grated Parmesan cheese (for topping)
- Optional: breadcrumbs (for extra crunch on top)
Substitutions and Variations:
- Ground Turkey or Chicken: You can substitute the ground beef with ground turkey or chicken for a leaner version of the meatloaf.
- Gluten-Free Option: Use gluten-free pasta for the mac and cheese, and substitute the breadcrumbs with gluten-free breadcrumbs.
- Dairy-Free Option: Replace the cheese and milk with dairy-free alternatives like almond milk and vegan cheese.
- Add Veggies: Incorporate finely chopped vegetables like carrots, spinach, or mushrooms into the meatloaf mixture for extra nutrients and flavor.
- Spicy Twist: Add a pinch of red pepper flakes or diced jalapeños into the mac and cheese sauce for a little heat.
Step-by-Step Cooking Instructions:

Step 1: Preheat Your Oven
Preheat your oven to 350°F (175°C). Grease a 9x13-inch casserole dish with cooking spray or a light coat of oil to prevent sticking.
Step 2: Prepare the Meatloaf Base
- In a large bowl, combine the ground beef, ground pork (if using), diced onion, breadcrumbs, milk, egg, Worcestershire sauce, garlic, salt, pepper, and oregano.
- Mix the ingredients thoroughly with your hands or a spoon until well combined.
- Press the meatloaf mixture evenly into the bottom of the prepared casserole dish, forming a compact layer.
- Optional: Spread a thin layer of ketchup over the top for a slight sweetness.
Step 3: Cook the Macaroni
- While the meatloaf base is resting, cook the elbow macaroni according to the package instructions. Drain and set aside.
Step 4: Make the Cheese Sauce
- In a medium saucepan, melt the butter over medium heat.
- Once melted, add the flour, stirring constantly for 2-3 minutes to form a roux (this thickens the sauce).
- Gradually whisk in the milk, continuing to stir until the mixture thickens.
- Stir in the mustard powder, garlic powder, salt, and pepper.
- Add the shredded cheddar cheese, stirring until melted and the sauce is smooth.
Step 5: Assemble the Casserole
- Pour the cooked macaroni into the cheese sauce and stir to coat the pasta evenly.
- Spread the mac and cheese mixture over the meatloaf base in the casserole dish.
- Sprinkle the grated Parmesan cheese (and optional breadcrumbs) over the top for a crispy, golden finish.
Step 6: Bake
- Place the casserole dish in the preheated oven.
- Bake for 40-45 minutes, or until the meatloaf is fully cooked (internal temperature should reach 160°F) and the cheese topping is bubbling and golden brown.
Step 7: Rest and Serve
- Remove the casserole from the oven and let it rest for 5-10 minutes before slicing.
- Serve warm and enjoy!
Common Mistakes to Avoid:
- Overmixing the Meatloaf: Overworking the meat mixture can result in a dense, tough meatloaf. Mix just until the ingredients are combined.
- Using Lean Meat: While you may want to cut calories, using too lean of meat can result in a dry meatloaf. A mix of beef and pork, or at least 85% lean ground beef, ensures a moist texture.
- Undercooking the Meatloaf: Always use a meat thermometer to ensure the meatloaf reaches an internal temperature of 160°F to ensure it’s fully cooked.
- Not Enough Cheese: Don’t skimp on the cheese! The mac and cheese layer is a key component, so be generous with your cheese to keep it creamy and rich.
Serving and Presentation Tips:
How to Serve Mac and Cheese Meatloaf Casserole:
- Family Style: Serve straight from the casserole dish, and let everyone dig in! This is a great dish for sharing.
- Portion Sizes: Slice the casserole into squares, just like lasagna, for easy, tidy servings.
- Accompaniments: Serve with a fresh green salad or steamed vegetables for a balanced meal. Garlic bread or dinner rolls also make a great side.
Presentation Ideas:
- Layered Look: Make sure your mac and cheese layer is clearly visible when slicing the casserole to show off the distinct layers of meatloaf and creamy pasta.
- Garnish: Add a sprinkle of fresh parsley or chives over the top for a pop of color and freshness.
- Individual Portions: For a fancier presentation, use individual ramekins to create personal-sized servings.
Mac and Cheese Meatloaf Casserole Recipe Tips:
- Cheese Choices: Feel free to experiment with different cheeses. Sharp cheddar is classic, but a blend of cheeses like Gouda, Monterey Jack, or even pepper jack can bring new flavors to the dish.
- Make-Ahead: This casserole can be assembled ahead of time. Just cover and refrigerate, then bake when you’re ready.
- Freezing: You can freeze leftovers for up to 3 months. Make sure to wrap it tightly in aluminum foil and reheat it in the oven for the best texture.
Frequently Asked Questions (FAQs):
- Can I use a store-bought mac and cheese mix?
- Yes, if you’re short on time, you can use a boxed mac and cheese mix. Just prepare it according to the instructions and use it in place of homemade mac and cheese.
- Can I freeze this casserole?
- Absolutely! After baking, let the casserole cool completely, then wrap it tightly and freeze. When ready to eat, thaw it overnight in the fridge and reheat in the oven.
- What can I use instead of breadcrumbs in the meatloaf?
- You can substitute breadcrumbs with crushed crackers, rolled oats, or even a small amount of cooked rice for a gluten-free option.
- How can I make this dish spicier?
- Add diced jalapeños or a dash of hot sauce to either the meatloaf or mac and cheese for a spicy kick.
Conclusion:
There you have it! A delicious, comforting Mac and Cheese Meatloaf Casserole that is sure to become a family favorite. This recipe brings together the best of two classic dishes, delivering layers of flavor and textures that everyone will love. Whether you’re making it for a special occasion or a weeknight dinner, it’s guaranteed to satisfy even the heartiest of appetites. Ready to try it out? Follow the steps above, and let us know how it turns out!
PrintMac and Cheese Meatloaf Casserole Recipe
Mac and Cheese Meatloaf Casserole combines classic cheesy mac with savory beef meatloaf. This all-in-one comfort dish is baked to perfection and ideal for family dinners. Perfect for meatloaf lovers seeking a cheesy twist!
- Prep Time: 20 minutes
- Cook Time: 45 minutes
- Total Time: 1 hour 5 minutes
- Yield: 6 servings
- Category: Main Course
- Method: Baking
- Cuisine: American
- Diet: Halal
Ingredients
- Ground beef
- Elbow macaroni
- Cheddar cheese
- Bread crumbs
- Milk
- Eggs
- Onion
- Garlic
- Worcestershire sauce
- Salt
- Pepper
Instructions
- Preheat oven to 350°F (175°C).
- Cook elbow macaroni and drain.
- In a bowl, mix ground beef, eggs, bread crumbs, onion, garlic, Worcestershire sauce, salt, and pepper to form the meatloaf mixture.
- Spread the meatloaf mixture evenly in a casserole dish.
- Layer cooked mac and cheese on top.
- Bake for 40-45 minutes until meat is cooked through and cheese is golden.
- Let cool slightly before serving.
Notes
- Use sharp cheddar for a bolder flavor.
- Add a dash of hot sauce or mustard for extra zest.
- Can substitute ground turkey or pork for beef.
Nutrition
- Serving Size: 1 serving
- Calories: 520 kcal
- Sugar: 4g
- Sodium: 900mg
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